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8.10 Biochemical effects Biochemical effects have been observed in cultured hepatocytes, liver homogenates and mitochondrial fractions, purified enzymes, isolated hepatic lipid membranes and whole liver preparations, including: metabolic effects on lipid peroxidation (Stege, 1982

doi: 10.1016/j.mcn.2015.03.007

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HEK293 cells were transiently transfected with full length proteins of LXR or LXR and their respective LBD domains under the pCMV-AD promoter(Stratagene)

Dose-proportional pharmacokinetics were observed following single dose intravenous administration of 2.5 to 10 g of hydroxocobalamin in healthy volunteers
doi:10.1136/bmj.1.5853.587
