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Whether it's due to dietary choices, digestive issues, or simply getting older, B12 deficiency is more common than you might think

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2022;219(4):e20211387

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Regarding the SEV group, B12-upregulated genes had GO annotations related to cytoplasmic translation (tRNA and rRNA processing), adaptive immune response, ncRNA processing, miRNA-mediated gene silencing, proteasome-mediated ubiquitin-dependent protein catabolic process, cobalamin transport, and negative regulation of transcription by RNA polymerase II ( Figure S3 )