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The biochemical in vitro reconstitution revealed the presence of characteristic [2Fe-2S] clusters on NEET proteins under anaerobic conditions, and these clusters were found to be redox active

While Lys-450 is involved in activity that is not dependent on flavin binding, His-447 and Trp-448 are either directly or indirectly involved in interactions with flavin

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T.GouletJ

doi: 10.3390/nu15194223