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Applications of Quantitative Structure-Activity Relationships (QSAR) based Virtual Screening in Drug Design: A Review

Our screening revealed the role of ZNF219 not previously described in cortical developmentin repressing neuronal differentiation, opposing roles for NR2E1 and ARX in regulating the balance of human excitatory versus inhibitory neurogenesis, and the role of ARX in safeguarding IN subtype specification through transcriptional repression of downstream transcription cofactor LMO1

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