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It has been investigated for its involvement in angiogenic signaling , where it is referenced in the literature as a modulator of vascular growth factor pathways

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Initial research suggested that the memory-enhancing effects often attributed to AngII were, in fact, mediated by its conversion to AngIV, acting at the AT4 receptor subtype

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Jika hal tersebut terjadi, maka bisa mengakibatkan kulit rusak serta menimbulkan tanda-tanda penuaan, seperti munculnya kerutan serta garis halus di wajah