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These results demonstrate that TSEL can improve cognitive deficits in APP/PS1 mice by acting synergistically with two genetic drugs to regulate the phenotype of activated microglia, reduce A accumulation, and prevent the re-triggering of neuroinflammation (Jiang et al., 2024)

In trials with semaglutide oral tablets, patients exposed to semaglutide 7 mg and 14 mg oral tablets had a mean increase from baseline in amylase of 10% and 13%, respectively, and lipase of 30% and 34%, respectively