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It is better understood as a stress-responsive metabolic signal that can move to the nucleus and influence gene-expression programs tied to energy balance

The stress-cortisol-sleep feedback loop where elevated cortisol disrupts sleep, and disrupted sleep elevates cortisol is being addressed at multiple points simultaneously

When assessing drug efficacy for the treatment of glioblastoma multiforme (GBM), currently, the most reliable models are generated through direct injection of patient-derived cells or more frequently the isolation of glioblastoma cells endowed with stem-like features and orthotopically injecting these cells into the cerebrum of immunodeficient mice

Low levels may contribute to fatigue, brain fog, and neurological symptoms

Uncertainty about the cause or significance of symptoms warrants medical consultation

10.1021/acsnano.4c12236 28 DaiS.YaoL.LiuL.CuiJ.SuZ.ZhaoA.et al (2024)