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Neuroimmunology of stress: Skin takes center stage

Additionally, busulfan can decrease Bcl-2 gene expression (as an antiapoptotic gene) and increase Bax gene expression (as a proapoptotic gene) in epididymal sperm of busulfan treated mice, which are related to increased oxidative stress as a result of decreased enzymatic antioxidants of GPx and SOD and increased level of lipid peroxidation in sperm cell (50)

TMAO might serve as a precise biomarker for conditions like mortality, cardiovascular diseases, diabetes, cancer, and kidney function [7]

This review provides a comprehensive update on the therapeutic potential of nutrients and presents new perspectives for combination supplements in DED treatment