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Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial

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Oral vitamin B12 treatment Since cobalamin is absorbed by intrinsic factor-independent passive diffusion, daily high-dose (pharmacological dose, 1,000 to 2,000 g [1 to 2 mg] per day) oral vitamin B12 (cyanocobalamin) can induce and maintain remission in patients with megaloblastic anemia [3,13]

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