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Description
At the pathophysiological level, two mechanisms underlie the formation of these pigmentations: (i) directly or indirectly inducing the synthesis and release of melanin by melanocytes, resulting in true pigmentation

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Arginine exerts its effect primarily through the metabolites NO and ornithine, which further take part in downstream reactions or are metabolized to bioactive molecules that take part in inflammation or the resolution of inflammation (Zhang et al., 2019)

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