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[DOI] [PMC free article] [PubMed] [Google Scholar] Tarnawski AS, Ahluwalia A

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Some peptides occur naturally, while others are synthesized using recombinant DNA technology to mirror the bodys own signaling compounds

In animal models, glial cells such as astrocytes and NG2 oligodendrocyte precursor cells can be directly converted into functional neurons in vivo via ectopic expression of neurogenic transcription factors like NeuroD1 and Ascl1

Neuroprotective and regenerative medicine approaches, including stem cell therapies and growth factor-based interventions, may eventually provide new treatment options