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While GHSR1a activity in the hypothalamus is likely heavily involved in homeostatic mechanisms, its presence in extra hypothalamic regions, including a number of limbic and midbrain structures like the ventral tegmental area (VTA), suggest that this receptor is associated in processes associated with learning and motivation (Abizaid et al., 2006

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Furthermore, the middle loop in SH3arr1-CC adopts an intermediate conformation between the fully active and fully inactive arr1 crystal structures (Fig

Supplementary material The Supplementary Material for this article can be found online at: References Akiyama S., Fukuda S., Steinberg J

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Bond, A