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Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway

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Vaessen N, Heutink P, Janssen JA, Witteman JCM, Testers L, Hofman A, Lamberts SWJ, Oostra BA, Pols HAP, Van Duijn CM

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AAS performed the experiments involving RNA interference, cytotoxicity assays, and helped with in vivo experiments

The role and interplay between these enzymes that prevent H 2 O 2 accumulation in the erythrocyte has been a topic of discussion over the years