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Both NP and spasticity are linked with common causal mechanisms like hypoactive inhibitory tone and neuronal hyperexcitability, which reduce the threshold and enhance responses of spinal neurons to non-painful stimuli

Recent advances in the modulation of pain by the metabotropic glutamate receptors

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Am J Gastroenterol 2002;97(8):2016-2021

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Patano N, Mancini L, Settanni MP, Strippoli M, Brunetti G, Greco G, Tamma R, Vergari R, Sardelli F, Koverech A, Colucci S, Zallone A, Grano M: L: -carnitine fumarate and isovaleryl-L: -carnitine fumarate accelerate the recovery of bone volume/total volume ratio after experimetally induced osteoporosis in pregnant mice