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The global hypermethylation silences TEs, while locus-specific promoter hypomethylation activates key transporters and chelators

The PCR products were quantified by PicoGreen fluorescence, and the cisplatin-treated (50 M) or BSO-treated samples (100 mM) were divided by control sample

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Administration routes Different peptides favor different administration routes, and the choice can significantly affect both bioavailability and the distribution of effects throughout the body

For the description of metabolism, most studies have been drawn from these two groups: constraint-based models (or stoichiometric models) and kinetic models (Gombert & Nielsen, 2000

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