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The synthetic pathway encompasses numerous enzyme-mediated transformations, including a crucial reaction catalyzed by -butyrobetaine hydroxylase (-BBH)

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Pastorino JG, Marcineviciute A, Cahill A, Hoek JB (1999) Potentiation by chronic ethanol treatment of the mitochondrial permeability transition