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doi: 10.1016/j.lfs.2021.120064 49 LiFYaoJHLiLNieQCaoJJNingXR

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Animal Model:Hyperreactive rats (male and female, 200-400 g, pretreated intravenously with 3 g/kg methysergide, 5 min before antigen chdlenge) [1] Dosage:0.5, 0.15, and 0.05 mg/kg Administration:Orally, once, 1 or 4 h before challenge Result:Produced dose-dependent inhibition of the duration of antigen-induced dyspnea, with ED 50 values of 0.13 (95% confidence interval (CI), 0.03-0.62) and 0.11 (95% CI, 0.009-1.47) mg/kg, respectively

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Long-term proteinuria will overload renal tubular protein reabsorption and accelerate renal fibrosis and renal failure (Bailey et al., 2022)

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Together, these peptides provide a structured framework for investigating coordinated signaling behavior across multiple receptor systems

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(Eds), UpToDate, Waltham, MA, 2012

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Glutathione has been shown to act as a depigmenting agent, for the treatment of human hyperpigmentation disorders

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