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doi: 10.1177/0300985815579994, PMID: [DOI] [PubMed] [Google Scholar] 113.Lim HY, Im KS, Kim NH, Kim HW, Shin JI, Sur JH
The inhibition kinetics and molecular modeling of these compounds showed that fixing the C4 and C5 hydroxyl groups in the diaxial conformation in the substrate mimic might be a good way to inhibit SK, due to the dramatic reduction in the flexibility of two domains(1) the SB domain (residues 917 in Mt-SK) and (2) the LID domain (residues 112124 in Mt-SK)
10.1146/annurev.neuro.051508.135531 Annu
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doi: 10.1146/annurev-nutr-080508-141048 3
Paradoxically, preliminary findings suggest that the KD may hold benefits for people with anorexia nervosa (AN)
