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Deficits in protein clearance, mitophagy, and lysosomal function contribute to neurodegeneration

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In recent years, a large number of studies have demonstrated that different types of cell death (including apoptosis, pyroptosis, necroptosis, and ferroptosis) occur concurrently in the progression of NAFL to NASH and that their occurrence correlates with the severity of the disease

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Interestingly, TBS activity is likely to induce elevated extracellular potassium levels