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The British Journal of Nutrition, 128 (9), 134

doi:10.1073/pnas.261709299

Specifically, the Patient Health Questionnaire (PHQ-9) score for depression dropped significantly from 13.03 to 9.84, and the Fibromyalgia Impact Questionnaire (FIQ) score dropped from 49.55 to 43.03
In all of these studies, ALCAR was found to have a noticeable effect on depression and helped improved moods and other cognitive impairments
(2017) ( Epub 2017 Aug 17 )

Possible signs include: Changes may develop slowly over time and may not cause symptoms initially
