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2) Characteristics of the population: sample size, groups, age, and diagnosis
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Moreover, TNF- can impact the function of other peripheral tissues, including the gastrointestinal tract, where it may modulate gut hormone secretion and nutrient absorption, consequently influencing appetite (8, 46)

These compounds are essential for maintaining gut health and have been shown to have several beneficial effects on the body, including reducing inflammation, improving insulin sensitivity, regulation of gene expression, and regulating the immune system (62, 65)

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