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doi: 10.3389/fcvm.2021.647785

[DOI] [PubMed] [Google Scholar] Fenves A

Bone mesenchymal stem cells co-expressing VEGF and BMP-6 genes to combat avascular necrosis of the femoral head

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In another study on human primary gastric TP53 / PDOs, knocking down the frequently mutated AT-rich interaction domain 1A ( ARID1A ) gene, led to a phenotype resembling ARID1A -mutant gastric cancers, particularly the MSI- (microsatellite instability) and (Epstein-Barr virus) EBV-associated subtypes, where ARID1A mutations are more common (Lo et al., 2021)

266 In HSCs and MuSCs, SIRT1 loss leads to premature cell differentiation, implicating it is a regulator of self-renewal of these cells