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All musculoskeletal findings come from animal models, primarily rodents

For example, the mimics may be administered prior to exposure to a drug, chemical or medical procedure that is known or likely to cause neuronal damage

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Cham: Springer International Publishing (2015) 846, 135

In addition, activation with DHK increases the threshold for lever pressing for electrical brain stimulation and increases the latency to begin consuming sucrose [173], all effects consistent with putative symptoms of anhedonia and opposite to the anti-depressant effects on the forced swim test described above [164]

Every vial requires a licensed provider to authorize the specific formulation, concentration, and quantity