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These shifts are compounded by impaired antioxidant defenses, including downregulation of GPX4 and system Xc - which diminish glutathione synthesis and the capacity to neutralize lipid hydroperoxides

Conclusions This review summarizes recent discoveries in ASD, particularly the connection to epigenetic regulation

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[DOI] [PMC free article] [PubMed] [Google Scholar] Yin Z, Ivanov V, Habelhah H, Tew KD and Ronai Z

McColl et al., 2010)

FIGURE 1 To identify relevant publications, independent searches of PubMed and Google Scholar were conducted using the term atrazine, with further refinements focusing on topics pertinent to this manuscript (e.g., testes, prostate, testosterone, inflammation, cancer)