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10.1016/S0083-6729(05)72004-5 85 MittlerR.HerrE

Rodriguez C, et al

DNA lesions disrupt this charge transfer, which changes the redox-active status of the ISC in DNA

Important aspects of high quality manufacturing include: ingredient verification to confirm the correct compound is present purity testing to remove contaminants or degraded molecules stability analysis to ensure the compound remains active over time manufacturing consistency so each dose delivers the same amount Poorly manufactured supplements may contain degraded molecules, inaccurate dosing, or contaminants that reduce both safety and effectiveness

But even if you and your veterinarian are able to get the underlying problem under control, the symptoms may not completely resolve because if left untreated, cobalamin deficiency causes vomiting, diarrhea, and weight loss

But remember, B12 shots and weight loss work best when combined with the right diet and regular exercise