what does glutathione does for cancer metabolism in progression and treatment resistance | Journal of Cell Biology Excessive glutathione intake contributes to

The chronically augmented leptin in the CNS contributes to leptin resistance, which further promotes obesity, resulting in a vicious cycle of escalating metabolic disorder

Research suggests that it may be associated with cytoprotective mechanisms and tissue repair processes in preclinical musculoskeletal, gastrointestinal, neurologic, and vascular injury models

The ER, which is responsible for essential cellular functions including protein folding and calcium storage/signaling, can experience disturbances in the folding environment, leading to the accumulation of misfolded proteins and subsequent ER stress

J Biol Chem 271(39):2391423919 Wu D, Cederbaum AI (2001) Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1

Before assuming the drug itself is the problem, check whether other factors might explain the stall , and inspect your vial carefully for any of the physical signs described above

Alliance 1 , e201800036 (2018)