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Risk of systemic copper overload is negligible when used as directed

Intrathecal administration of riluzole dose-dependently attenuated the decreased electroacupuncture analgesia, strongly suggesting involvement of spinal EAATs in the electroacupuncture effect [413]

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Chronic NMDA exposure accelerates development of GABAergic inhibition in the superior colliculus

Several potential neuroprotective targets have shown promise in preclinical studies, but failed to demonstrate efficacy in clinical trials, despite their effects on IOP and/or neuroprotection ( The term neuroprotection in the context of glaucoma refers to methods aimed at preventing damage and degeneration of RGCs and their axons, which are key features of the disease

Sufficient B12 is important for maintaining cognitive health and preventing various forms of cognitive impairment