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The side chains of the Glu, Try, and Asp residues form a highly nucleophilic region in the enzymes active center, where oxidation of the active site selenocysteine (RSeH) or cysteine (RSH) occurs after binding the peroxide

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10.2174/1389557520666200429103225 24 FangC.PanJ.QuN.LeiY.HanJ.ZhangJ.et al (2022a)

Recently, Ravaioli M et al

While oral vitamin C supplements are widely available, IV therapy bypasses the digestive system, ensuring higher absorption rates and faster effects