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aureus osteomyelitis activates platelets via neutrophil secretion products
[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Foxman B
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After the macrophages ingest MSU through the phagocytic pathway, NLRP3 inflammasome assembly and activation are triggered, and the generated complex consists of NLRP3, the adaptor protein apoptosis-related cyclin-like protein (ASC), and caspase-1 (53)

For example, the penis might be damaged during sex, athletic activity or as the result of an accident
