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The use of pharmacological agents that increase HO-1 expression, and therefore its metabolites (carbon monoxide, biliverdin and bilirubin) can become a therapeutic strategy for handling different inflammatory diseases (24)

The researchers showed that these compounds prevented cells from BaP-induced cell cycle arrest and growth inhibition, significantly suppressed BaP-induced ROS levels, and decreased BPDE-I DNA adducts

Kumar V, Kundu S, Singh A, Singh S

GPx-1 and response to in vivo ROS Consistent with increased apoptosis and cell death of isolated cells grown in culture, lack of GPx-1 in vivo sensitizes mice to death in response to the oxidant generators, diquat and paraquat (89, 135, 371)

doi: 10.3390/ijms251810151, 35 SongC.HeD.YangZ.FuY.ZhengH.XingZ.et al

The ability of taninins to protect the liver from damage caused by APAP has also been looked into