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Glycine cleavage system, reaction mechanism, physiological significance, and hyperglycinemia

doi: 10.1155/2020/1359164

Following long-term treatment of leptin-deficient ob/ob mice with E2, levels of STAT3 and phosphorylated STAT3 on tyrosine 705 in the liver increase, downregulating the expression of lipogenic genes ATP-citrate lyase, and fatty acid synthase (53)

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Ailuno G, Baldassari S, Balboni A, Drava G, Spalletti C, Tantillo E, et al