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Through conjugation with the DOTA chelator and subsequent radiolabeling with the positron-emitting radionuclide copper-64 ( 64 Cu), daratumumab has been successfully developed as a molecular probe targeting CD38-expressing MM cells [102]

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The microorganisms propionibacterium freudenreichii and pseudomonas denitrificans produce vitamin B12 when they grow in a nutrient medium which provides glucose nitrogen sources and cobalt salts

Another important consideration is that high-dose folic acid can mask the haematological signs of B12 deficiency while allowing neurological damage to progress