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Total serum holo-transcobalamin Dietary B 12 is transported in the digestive system via the use of three protein transporters that bind the micronutrient in a sequential fashion, following the order haptocorrin (HC), intrinsic factor (IF), and transcobalamin (TC) (Fedosov et al., 12 bound to TC (holo-TC) reaches circulation and it is distributed to every cell in the body

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