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Description
Only 12% of an oral crystalline dose of non-protein bound vitamin B12 as occurs in fortified foods and supplements is absorbed by simple passive diffusion throughout the length of the gastrointestinal tract (Doets et al., 2013)

This effect on heart rate is an important safety issue that needs special attention in future trials since obese individuals are at increased cardiovascular risk

Wallace DC

those continuing on semaglutide 2.4 mg achieved a 7.9% BW reduction at study end, while patients on placebo exhibited a BW gain of 6.9% 25

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