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Pediatr Radiol 2008;38(5):559-62

Topical copper tripeptide application in irradiated tissue models restored fibroblast activity and collagen deposition comparable to non-irradiated controls

While it did at first appear surprising that p53 but not ATM was required for reducing histone levels in response to chronic irradiation, we noted that p53 protein was upregulated, with concomitant increase of its downstream target p21, in chronically irradiated RPE-1 cells independently of ATM status (Fig

In the hair bulb, IRF4 appears to act on the differentiation and survival of melanocytes

The secretion of TNF- by resting human peripheral T-cells also increased in response to D1/D5 and D3 activation (Besser et al., 2005)

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