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Peer review Peer review information Nature Communications thanks Brian Pierce and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

However, in a subsequent 24-week trial involving 536 obese participants, AOD 9604 did not achieve statistically robust, clinically meaningful weight-loss outcomes versus placebo, and the obesity-drug development program was discontinued around 2007

Motawe ZY, Abdelmaboud SS, Cuevas J, Breslin JW

Kapitsinou, P

Placebo provoked subclinical mild bronchoconstriction (changes from baseline: FEV 1 , 2 1%

Adiponectin levels are diminished by sickness
