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2 The three most widely used sequences to date come from proteins with brain tropism and include: Angiopep-2, which was derived from the Kunitz domain of several proteins and targets low-density lipoprotein receptor-related protein 1 (LRP1)

8 Conclusion The convergence of circadian biology and aging research reveals time not merely as a backdrop but as a dynamic biological force, where Kronos , that represents the linear progression of age, and Kairos , the opportune moment dictated by biological rhythms, co-determine the trajectory of health and disease

Zhang et al 163 reported that gallic acid (GA) and Fe 2+ NPs (GFNPs) form a drug platform in which DOX is loaded by electrostatic adsorption with DSPE-PEG-Pt(IV), and the targeting moiety DSPE-PEG(2000) is coated on the surface with cRGD

[30] Engelmann C, Sheikh M, Sharma S, Kondo T, Loeffler-Wirth H, Zheng YB, et al

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