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Options include: Fortified foods : Nutritional yeast, plant-based milk alternatives, breakfast cereals, and meat substitutes fortified with B12 (check labels for content) Supplements : Daily supplements of 10 mcg or weekly doses of 2,000 mcg ensure adequate intake, as recommended by the British Dietetic Association The body absorbs approximately 50% of a 12 mcg dose but only about 1% of a 1,000 mcg dose through passive diffusion

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In the SURMOUNT-1 trial with 2,539 adults with obesity, participants on the highest tirzepatide dose (15 mg weekly) lost an average of 20.9% of their body weight over 72 weeks
Despite limited research on the association between NNMT and hyperlipidemia, compelling evidence suggests its potential role in lipid metabolism

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