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In active relapsing-remitting multiple sclerosis, effector T cell resistance to adaptive T(regs) involves IL-6-mediated signaling

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S-adenosylhomocysteine is formed by the demethylation of SAMe (Figure 54-2)

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Emerging evidence suggests that disruptions to the early microbiomedue to antibiotic exposure, poor maternal diet, or lack of breastfeedingcan alter synaptic pruning, neurotransmitter systems, and stress reactivity in ways that may predispose individuals to cognitive deficits and mood disorders later in life