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Given the functional role of SLC6A14 in extending the range of amino acid uptake (including glutamine and leucine, both of which are activators of mTORC1), as well as providing substrates for SLC1A5 and SLC7A5, the molecule has attracted much attention 99,100

Mol Med Camb Mass 30(1):15

Additionally, accelerated ATP degradation under pathological conditions (e.g., intense exercise and ischemiareperfusion injury) promotes hypoxanthine accumulation, creating a secondary drive for UA overproduction (Uskudar Cansu et al., 2019)

Temporal analyses of the response of intervertebral disc cells and mesenchymal stem cells to nutrient deprivation

Its cardiotoxicity-diminishing activity seems to be due to the removal of iron from ironanthracycline complexes, and thus it may reduce free radical formation
