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It has been reported that K-Ras-driven mouse lung tumors preferentially utilize glucose more than glutamine to supply carbon to the TCA cycle via pyruvate carboxylase 192
The in vitro biological effects of CB-839 have been tested more extensively in multiple myeloma (24), AML (10, 11), and T-cell acute lymphoblastic leukemia cell lines and primary blasts (29)
A 10% KOH solution was used to aid digestion
In this assay, we analyzed the impact of ENDO series on CpG-induced TLR9 activation using cells expressing the human TLR9 gene upstream of an inducible and secretable embryonic alkaline phosphatase (SEAP) reporter system
10.1097/md.0000000000022841 143 SunakawaY.StintzingS.CaoS.HeinemannV.CremoliniC.FalconeA.et al (2015)
