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Animal data is a necessary first step, but its far from sufficient on its own to draw conclusions about a drugs effectiveness and safety in humans

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MOTS-c has a plasma half-life of approximately 2 hours, but its metabolic effects persist for 68 hours due to downstream signalling cascades

doi: 10.1177/0961203314556138]

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Quick Answer: Semaglutide injected into muscle tissue may cause increased pain and altered absorption, though this route was not studied in clinical trials and is not FDA-approved