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Individuals with reduced activity of the DHFR enzyme, which is responsible for the first step in folic acid metabolism, may be less able to convert folic acid efficiently

Systematic reviews and comparative PK studies confirm that specialized curcumin preparations can increase systemic exposure versus unformulated curcumin, but the magnitude of the increase depends strongly on formulation type, dose, and the analytic method used to quantify free versus conjugated curcuminoids

Intrauterine exposure to dexamethasone impairs proliferation but not neuronal differentiation in the dentate gyrus of newborn common marmoset monkeys