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Non-CYP drug metabolizing enzymes and their reactions

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View Abstract Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines

Two inherited diseases in the carnitine biosynthetic pathway have been reported (deficiency of 6- N -trimethyllysine dioxygenase and deficiency of -butyrobetaine dioxygenase), which result in only mildly decreased to normal carnitine levels in the affected patients [60, 61]

CBD activates five TRP channels, including TRPV1, TRPV2, TRPV3, TRPV4, and TRPA1, and antagonizes TRPM8 (Table 2, Fig