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Description
Prior to exclusion, the I statistic suggested moderate heterogeneity
H.LehkyT.ThomasR
In summary, our results suggest that electrophilic compounds can expand the range of available senolytic targets
B.HorieT.LuoW.XuG.SchroederJ
For instance, in an IL-1-stimulated chondrocyte OA model and a surgically induced OA rat model, exosomes derived from OA patient FLS were found to reduce chondrocyte viability, GSH/GSSG ratio, GPX4, SLC7A11, and MMP levels
It can also regulate a number of inflammatory cells, including neutrophils, macrophages, and T cells, assisting in responding to injury or infection
