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125,126 Other than intracellular lactate metabolism, lactate may be transported into target cells via nonchannel pathways or MCTs through intercellular shuttling

Molecular size, enzymatic degradation, saliva, short contact time, and the mucosal barrier can all limit uptake

Silk et al

Neptun showed an increased expression of glutathione transferase StGSTF2 and a general activity of GST, corresponding with an increase in the GSSG form and indicating involvement in the resistance reaction

Repeated use of D51.9 without progression to a specific code signals incomplete workup and reduces reimbursement

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