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doi: 10.1016/j.apsb.2023.05.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 405

The results of in vivo pharmacokinetic studies also revealed similar findings where the maximum plasma drug concentration ( C max ), area under curve (AUC) and absorption rate constant ( K a ) of dispersion were increased by 5.14, 6.46 and 1.91 times, respectively, as compared to pure drug

Increased GST activity has been observed in patients with chlorambucil-resistant chronic lymphocytic leukemia [51]

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To confirm further the structural integrity of the SRCRD protein and whether the disulfide bonds in the protein were formed correctly after refolding, the crystallization experiments of SRCRD were performed using the sitting-drop vapor diffusion method