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Simultaneous Quantification of TB-500 and Its Metabolites in In-Vitro Experiments and Rats by UHPLC-Q-Exactive Orbitrap MS/MS and Their Screening by Wound Healing Activities In-Vitro, Rahaman KA, Muresan AR, Min H, Son J, Han HS, Kang MJ, Kwon OS, Journal of Chromatography B, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2024;1235:124033

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Both human IgM and IgG1 were observed in serum samples from these transgenic mice, and the study revealed that antibody class switching from IgM to IgG1 could occur in this transgenic model [109]