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Pangkahila, W
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FIGURE 1 2.1 A plaque hypothesis The amyloid cascade hypothesis, the most recognized hypothesis to date, was proposed by British scientists Hardy and Higgins (1992)

PLoS ONE 9(1):e82331

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With this perspective, Daughaday et al.[5, 42] proposed the somatomedin hypothesis for the postnatal growth, where GH stimulated skeletal growth by stimulating liver production of IGF-I, which in turn promotes longitudinal bone growth in an endocrine manner
