glutathione reaction mechanism Frontiers Glutathione-Mediated Conjugation of Anticancer Drugs:
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doi: 10.1016/j.intimp.2020.106909 [DOI] [PubMed] [Google Scholar] 223.Faust HJ, Zhang H, Han J, et al

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Given the similarities in how the human and rat GCLC respond to oxidative stress, whether oxidative stress can increase c-Myc binding to this E-box and displace USF1/2 to activate rat GCLC would be of interest

Longer studies are needed
